Hendaya Kognitif pada Penderita HIV

Oleh :

dr.Soeklola Muliady SpKJ

Hendaya kognitif banyak dialami oleh pasien HIV. Hal ini merupakan bagian dari komplikasi sistem saraf pusat yang disebut sebagai HIV-associated neurocognitive disorders (HAND). Prevalensi gangguan kognitif pada pasien HIV telah dilaporkan mencapai 39,6% dan merupakan morbiditas yang sering tidak mendapat cukup perhatian dalam penanganan kasus HIV.[1-4]

Mekanisme Terjadinya Hendaya Kognitif pada Penderita HIV

Dahulu, sebelum penelitian terkait HIV semaju saat ini, pasien HIV sering mengalami berbagai masalah yang dapat menyebabkan efek jangka panjang pada otak, seperti infeksi sistem saraf pusat, kanker, dan toksisitas dari obat antiretroviral generasi awal. Selain itu, pada perjalanan penyakitnya, terdapat berbagai proses yang berhubungan dengan gangguan kognitif pada pasien HIV, termasuk neuroinflamasi, atrofi otak, dan cedera neuron.

(Konten ini khusus untuk dokter. Registrasi untuk baca selengkapnya)

Referensi

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