Pengembangan Vaksin COVID-19

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Pengembangan vaksin COVID-19 menjadi salah satu pendekatan yang dipertimbangkan untuk mengatasi wabah SARS-CoV-2. Serupa dengan teknik pengembangan vaksin MERS (Middle East Respiratory Syndrome) dan SARS, sejumlah teknik pengembangan vaksin coronavirus menggunakan DNA, mRNA, protein rekombinan, dan vektor adenovirus kini sedang banyak dipelajari. Penggunaan teknik yang menargetkan protein S dan protein lain yang terkait (misalnya, protein N, S1, S2, dan RBD) juga dapat dipertimbangkan sebab protein semacam ini juga menjadi target dalam pengembangan vaksin MERS dan SARS.

Sejak penyebaran informasi tentang urutan genetik SARS-CoV-2 pada pertengahan Januari 2020, berbagai institusi akademik dan perusahaan farmasi di seluruh dunia telah terlibat dalam pengembangan vaksin penyakit COVID-19 dan beberapa kandidat vaksin telah mencapai tahap evaluasi efikasi pada uji pada hewan coba serta uji klinis. Dalam artikel ini akan dibahas tentang gambaran umum pengembangan vaksin COVID-19, penelitian in vivo terkait vaksin COVID-19, dan potensi penggunaan vaksin lain sebagai vaksin COVID-19.

Gambaran Umum Pengembangan Vaksin COVID-19

Jenis-jenis vaksin COVID-19 yang sedang dikembangkan saat ini:

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