Peran Thyroid Scintigraphy dalam Mendiagnosis Kelainan Tiroid

Oleh :

dr. Ivana Dewi Mulyanto, SpKN(K), MKes, FANMB

Thyroid scintigraphy atau sidik tiroid merupakan salah satu pemeriksaan fungsional di kedokteran nuklir yang diindikasikan untuk menilai aktivitas kelenjar tiroid. Pemeriksaan fungsional berbeda dari pemeriksaan morfologi, seperti ultrasonografi (USG). Dasar pemahaman mengenai metabolisme iodin, fisiologi, dan patofisiologi tiroid penting dalam menginterpretasi sidik tiroid.[1–3,11]

Metabolisme dan Fisiologi Yodium

Iodin merupakan bahan utama sintesis hormon tiroid. Iodin dengan cepat diubah menjadi iodida pada usus kecil bagian proksimal, kemudian lebih dari 90% akan diserap dalam waktu 60 menit. Kelenjar tiroid mengkonsentrasikan iodida dengan mekanisme transpor aktif iodida dari sirkulasi darah ke dalam koloid. Mekanisme transpor tersebut sering disebut iodide trapping mechanism atau pompa iodida.

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